Metabolic dephenylation of the rubber antioxidant N in Russia

metabolic dephenylation of the rubber antioxidant n -phenyl-2 ...

Metabolic dephenylation of the rubber antioxidant N -phenyl-2 ...

N-Phenyl-2-naphthylamine (P2NA) was widely used as oxidation inhibitor, particularly in rubber manufacturing. Technical-grade P2NA was contaminated with carcinogenic 2-naphthylamine (2NA), and bladder cancer risk in exposed workers was attributed to this impurity. Investigations in humans and mammalian species revealed that small amounts of 2NA are excreted into urine after exposure to P2NA ...

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metabolic dephenylation of the rubber antioxidant n-phenyl-2 ...

Metabolic dephenylation of the rubber antioxidant N-phenyl-2 ...

Metabolic dephenylation of the rubber antioxidant N-phenyl-2-naphthylamine to carcinogenic 2-naphthylamine in rats. Weiss T(1), Bolt HM, Schlüter G, Koslitz S, Taeger D, Welge P, Brüning T.

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metabolic dephenylation of the rubber antioxidant n-phenyl-2 ...

Metabolic dephenylation of the rubber antioxidant N-phenyl-2 ...

Archives of toxicology 2013-2-21 Metabolic dephenylation of the rubber antioxidant N-phenyl-2-naphthylamine to carcinogenic 2-naphthylamine in rats. [Tobias Weiss, Hermann M Bolt, Gerhard Schlüter, Stephan Koslitz, Dirk Taeger, Peter Welge, Thomas Brüning]

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(pdf) metabolic dephenylation of the rubber antioxidant n ...

(PDF) Metabolic dephenylation of the rubber antioxidant N ...

Metabolic dephenylation of the rubber antioxidant N-phenyl-2-naphthylamine to carcinogenic 2-naphthylamine in rats Article (PDF Available) in Archives of Toxicology 87(7) · February 2013 with 39 ...

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(pdf) metabolic dephenylation of the rubber antioxidant n ...

(PDF) Metabolic dephenylation of the rubber antioxidant N ...

Metabolic dephenylation of the rubber antioxidant N-phenyl-2-naphthylamine to carcinogenic 2-naphthylamine in rats

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metabolic dephenylation of the rubber antioxidant n-phenyl-2 ...

Metabolic dephenylation of the rubber antioxidant N-phenyl-2 ...

Metabolic dephenylation of the rubber antioxidant N-phenyl-2-naphthylamine to carcinogenic 2-naphthylamine in rats By Tobias Wei\udf, Hermann M. Bolt, Gerhard Schl\ufcter, Stephan Koslitz, Dirk Taeger, Peter Welge and Thomas Br\ufcning

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dephenylation of n -phenyl-2-naphthylamine in dogs and its ...

Dephenylation of N -phenyl-2-naphthylamine in dogs and its ...

N-Dephenylation of N-phenyl-2-naphthylamine (PBNA) is strictly limited in dogs, and a 5 mg/kg dose gives 0-10 microng of urinary 2-naphthylamine (BNA), which does not appear to undergo further ...

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comparative n-dephenylation of n-phenyl-2-naphthylamine

Comparative N-dephenylation of N-phenyl-2-naphthylamine

The Society of Dyers * Correspondence about this article should be addressed to, Dr. S. Laham, Occupational Toxicology Research Section 657 658 and Colourists indicates that this compound has been mostly used as a chemical intermediate in the production of the rubber antioxidant, N-phenyl-2-naphthylamine-acetone condensate and in the production ...

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metabolic dephenylation of the rubber antioxidant n-phenyl-2 ...

Metabolic dephenylation of the rubber antioxidant N-phenyl-2 ...

Metabolic dephenylation of the rubber antioxidant N-phenyl-2-naphthylamine to carcinogenic 2-naphthylamine in rats By Tobias Wei\udf, Hermann M. Bolt, Gerhard Schl\ufcter, Stephan Koslitz, Dirk Taeger, Peter Welge and Thomas Br\ufcning

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comparative n-dephenylation of n-phenyl-2-naphthylamine

Comparative N-dephenylation of N-phenyl-2-naphthylamine

The Society of Dyers * Correspondence about this article should be addressed to, Dr. S. Laham, Occupational Toxicology Research Section 657 658 and Colourists indicates that this compound has been mostly used as a chemical intermediate in the production of the rubber antioxidant, N-phenyl-2-naphthylamine-acetone condensate and in the production ...

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dephenylation of n-phenyl-2-naphthylamine in dogs and its ...

Dephenylation of N-phenyl-2-naphthylamine in dogs and its ...

Metabolic dephenylation of the rubber antioxidant N-phenyl-2-naphthylamine to carcinogenic 2-naphthylamine in rats. Weiss T, Bolt HM, Schlüter G, Koslitz S, Taeger D, Welge P, Brüning T. Arch Toxicol, 87(7):1265-1272, 20 Feb 2013 Cited by: 3 articles | PMID: 23423714

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ipa - tobias weiß, phd

IPA - Tobias Weiß, PhD

Weiß T, Bolt HM, Schlüter G, Koslitz S, Taeger D, Welge P, Brüning T. Metabolic dephenylation of the rubber antioxidant N-phenyl-2-naphthylamine to carcinogenic 2-naphthylamine in rats. Arch Toxicol. 2013; 87: 1265-7

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biotransformation of n-phenyl-β-naphthylamine to β ...

Biotransformation of N-phenyl-β-naphthylamine to β ...

N-Phenyl-β-naphthylamine, a widely used rubber antioxidant and antiozonant, was biotransformed into β-naphthylamine, a potent carcinogen, in a laboratory sewage sludge system. β-Naphthylamine appeared to accumulate in the aqueous phase of the system while the undegraded parent compound appeared to be associated with the sludge solids.

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n‐phenyl‐2‐naphthylamine [mak value documentation, 2011 ...

N‐Phenyl‐2‐naphthylamine [MAK Value Documentation, 2011 ...

Abstract The article contains sections titled: Skip to Article Content; Skip to Article Information

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carcinogenicity of /v-phenyl-1-naphthylamme and jv-phenyl- 2 ...

Carcinogenicity of /V-Phenyl-1-naphthylamme and JV-Phenyl- 2 ...

other routes of metabolic activation besides dephenylation for both chemicals in mice. INTRODUCTION After confirmation of the carcinogenicity of PBNA2 in animals, its optic isomer, PANA, was tested for its carcinogenicity in comparison with that of PBNA in 2 animal models (7-11). It was found that PANA, also an antioxidant used in the rubber ...

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n-phenyl-2-naphthyl amine, 135-88-6

N-phenyl-2-naphthyl amine, 135-88-6

PubMed:Dephenylation of the rubber chemical N-phenyl-2-naphthylamine to carcinogenic 2-naphthylamine: a classical problem revisited. PubMed: Effect-directed analysis of key toxicants in European river basins a review.

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jianyao wang's research works | janssen research ...

Jianyao Wang's research works | Janssen Research ...

Reference: Metabolic dephenylation of the rubber antioxidant N-phenyl-2-naphthylamine to carcinogenic 2-naphthylamine in rats Mechanism Study of N-Dephenylation Mediated through a N-para-Hydroxy ...

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2-naphthylamine - chemical agents and related occupations ...

2-NAPHTHYLAMINE - Chemical Agents and Related Occupations ...

2-Naphthylamine was considered by previous IARC Working Groups in 1973, 1987, and 2008 (IARC, 1974, 1987, 2010). Since that time new data have become available, which have been incorporated in this Monograph, and taken into consideration in the present evaluation.

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n-phenyl-2-naphthyl amine, 135-88-6

N-phenyl-2-naphthyl amine, 135-88-6

PubMed:Dephenylation of the rubber chemical N-phenyl-2-naphthylamine to carcinogenic 2-naphthylamine: a classical problem revisited. PubMed: Effect-directed analysis of key toxicants in European river basins a review.

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appendix 8: n-phenyl-beta-naphthylamine | spacecraft water ...

Appendix 8: N-Phenyl-beta-naphthylamine | Spacecraft Water ...

N-Phenyl-beta-naphthylamine TABLE X-1 Physical and Chemical Properties 291 Formula COHEN Synonyms PNA, N-phenyl-2-naphthylamine, 2-napthalen- amine, N-phenyl, N-~2-naphthyl) aniline, 2- H a n i 1 i n 0 n a p h t h a 1 i n e , b e t a - n a p h t h y 1 p h e n y 1 a m i n e , / \ Agerite powder, Neozone-D, Antioxidant 1 16 CA 135-88-6 S registry ...

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antioxidant

Antioxidant

The relative importance of the antioxidant and pro-oxidant activities of antioxidants is an area of current research, but vitamin C, which exerts its effects as a vitamin by oxidizing polypeptides, appears to have a mostly antioxidant action in the human body.

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the united states rubber anti-aging antioxidant ippd(4010na ...

the united states rubber anti-aging antioxidant ippd(4010na ...

rubber antioxidant 6ppd ippd, rubber antioxidant 6ppd ippd . Antioxidant 4010NA (IPPD) Chemical Name: N-isopropyl-N'-phenyl-p-phenylenediamine Structural Formula: Molecular Formula : C15H18N2 Molecular Weight : 226.3 CAS#: 101-72-4 Spec. Item Spec. Usage : It is widely used to manufacture tyres, rubber tuber, belts, shoes, fibre, normal industrial rubber products, Storage: The product should ...

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the chemistry behind antioxidant capacity assays | journal of ...

The Chemistry behind Antioxidant Capacity Assays | Journal of ...

This review summarizes the multifaceted aspects of antioxidants and the basic kinetic models of inhibited autoxidation and analyzes the chemical principles of antioxidant capacity assays. Depending upon the reactions involved, these assays can roughly be classified into two types: assays based on hydrogen atom transfer (HAT) reactions and assays based on electron transfer (ET). The majority of ...

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biomonitoring of aromatic amines vi: determination of ...

Biomonitoring of aromatic amines VI: determination of ...

Metabolic dephenylation of the rubber antioxidant N-phenyl-2-naphthylamine to carcinogenic 2-naphthylamine in rats. Weiss T, Bolt HM, Schlüter G, Koslitz S, Taeger D, Welge P, Brüning T. Arch Toxicol, 87(7):1265-1272, 20 Feb 2013 Cited by 3 articles | PMID: 23423714

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frontiers | antioxidant role of pcgstd1 in fenpropathrin ...

Frontiers | Antioxidant Role of PcGSTd1 in Fenpropathrin ...

However, its antioxidant role in alleviating the oxidative stress caused by fenpropathrin was demonstrated via the reversely genetic experiment. Our results provide a list of candidate genes which may contribute to a multiple metabolic mechanisms implicated in the evolution of fenpropathrin resistance in the field population of P. citri.

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metabolism

Metabolism

Metabolism (/ m ə ˈ t æ b ə l ɪ z ə m /, from Greek: μεταβολή metabolē, "change") is the set of life-sustaining chemical reactions in organisms.The three main purposes of metabolism are: the conversion of food to energy to run cellular processes; the conversion of food/fuel to building blocks for proteins, lipids, nucleic acids, and some carbohydrates; and the elimination of ...

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lignin as alternative reinforcing filler in the rubber ...

Lignin as Alternative Reinforcing Filler in the Rubber ...

The prospects of plants such as dandelion as an alternative natural rubber source look brighter because of its inherent natural rubber potential and its metabolic processes, which affect the rubber synthesis and became the focus of study with the aim of enhancing its annual productivity (Laibach et al., 2015). In the 1930s−1950s, Russian ...

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the chemistry behind antioxidant capacity assays | journal of ...

The Chemistry behind Antioxidant Capacity Assays | Journal of ...

This review summarizes the multifaceted aspects of antioxidants and the basic kinetic models of inhibited autoxidation and analyzes the chemical principles of antioxidant capacity assays. Depending upon the reactions involved, these assays can roughly be classified into two types: assays based on hydrogen atom transfer (HAT) reactions and assays based on electron transfer (ET). The majority of ...

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improvement and utilization of natural rubber- and castor oil ...

Improvement and Utilization of Natural Rubber- and Castor Oil ...

Domestic production of both castor and rubber has taken place in the past, yet critical issues denied sustainability of these important industrial crops. We propose to address these via the following objectives: Objective 1: Develop germplasm that enables domestic commercial production of natural rubber and ricinoleate by metabolic engineering ...

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biomonitoring of aromatic amines vi: determination of ...

Biomonitoring of aromatic amines VI: determination of ...

Metabolic dephenylation of the rubber antioxidant N-phenyl-2-naphthylamine to carcinogenic 2-naphthylamine in rats. Weiss T, Bolt HM, Schlüter G, Koslitz S, Taeger D, Welge P, Brüning T. Arch Toxicol, 87(7):1265-1272, 20 Feb 2013 Cited by 3 articles | PMID: 23423714

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biobased contents of natural rubber model compound and its ...

Biobased Contents of Natural Rubber Model Compound and Its ...

Production of rubber products with biobased constituents from biomass resources is desirable for conserving our planet’s limited resources and preventing global warming. Herein, a natural rubber model compound was produced to determine the biobased contents as per various indices for calculating the amount of biomass resources used in rubber products. The biobased mass and biobased carbon ...

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global natural food antioxidants market size, 2028 | industry ...

Global Natural Food Antioxidants Market Size, 2028 | Industry ...

Antioxidants are a type of chemical that helps in rebelling the hypothetically damaging effects of unhinged substances, which are known as free radicals. These free radicals are compounds that are molded when the body is at its normal metabolic process and has general wear and tear on body cells.

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