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disulfiram - pkg of 1 g | tetd | sigma-aldrich

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Disulfiram Pharmaceutical Secondary Standard; Certified Reference Material Synonym: Bis(diethylthiocarbamoyl) disulfide, Bis(diethylthiocarbamyl) disulfide, Disulfiram, TETD, Tetraethylthiuram disulfide CAS Number 97-77-8. Linear Formula (C 2 H 5) 2 NCSS 2 CSN(C 2 H 5) 2. Molecular Weight 296.54 . Beilstein/REAXYS Number 1712560 .

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disulfiram | sigma-aldrich

Disulfiram | Sigma-Aldrich

Disulfiram 4 Products Synonym: Bis(diethylthiocarbamoyl) disulfide, Bis(diethylthiocarbamyl) disulfide, Disulfiram, TETD, Tetraethylthiuram disulfide

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Disulfiram (tetraethylthiuram disulfide [TETD]) has been used for more than 50 years as a deterrent to ethanol abuse in the management of alcoholism. Approximately 200,000 alcoholics take disulfiram, or Antabuse, regularly in the United States.

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disulfiram (synonyms: tetraethylthiuram disulfide; tetd)

Disulfiram (Synonyms: Tetraethylthiuram disulfide; TETD)

Disulfiram (Tetraethylthiuram disulfide) is a specific inhibitor of aldehyde-dehydrogenase (ALDH1), used for the treatment of chronic alcoholism by producing an acute sensitivity to alcohol. Disulfiram inhibits gasdermin D (GSDMD) pore formation in liposomes and inflammasome-mediated pyroptosis and IL-1β secretion in human and mouse cells. - Mechanism of Action & Protocol.

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Disulfiram resulted in very high, but transient, plasma levels. Small, repeated oral doses of disulfiram would be just as effective in nickel carbonyl poisoning as a single large dithiocarb dose. However, disulfiram increase the nickel retained in brain tissue, possibly accounting for its limited efficacy. Caution in the use of oral disulfiram ...

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• Disulfiram • Disulfirame • Disulfirame [DCIT] • Disulfiramo • Disulfiramo [INN-Spanish] • Disulfiramum • Disulfiramum [INN-Latin] • Dupon 4472 • Dupont fungicide 4472 • EINECS 202-607-8 • ENT 27,340 • Ekagom DTET • Ekagom TEDS • Ekagom TETDS • Ephorran • Esperal • Esperal [France] • Etabus • Ethyl TUEX ...

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Disulfiram, tetraethylthiuram disulfide (TETD), was synthesized from thiocarbamide in the 1880s to accelerate the vulcanization (stabilization) of rubber by the addition of sulfur. 108 Sixty years later, it was the first Western medication used to treat alcohol dependence.

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97-77-8 Disulfiram. Min.Order: 1 Kilogram FOB Price: USD $ 0.0-0.0/Kilogram Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.

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Disulfiram, USP is used to treat chronic alcoholism by creating acute sensitivity to alcohol in the body. All Spectrum Chemical USP grade products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.

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Abstract. At the outset the difference between alcoholic intoxication and the alcohol withdrawal syndrome must be clarified. Intoxication is the well-known clinical effect of alcohol on the body, mediated through its tranquilizing and sedating effect on the central nervous system, beginning with mood changes and progressing through psychomotor retardation and reflex slowing to lethargy and sleep.

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TETD is a rubber accelerator of the thiuram group, contained in “thiuram mix.” It can cross-react with other thiurams, especially TMTD. TETD is used to aid those trying to break their dependence on alcohol. The disulfiram-alcohol reaction is not allergic but due to the accumulation of toxic levels of acetaldehyde.

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The tetraethylthiuramdisulfide * (Antabuse)-alcohol reaction is an essential element in the indoctrination of the patient in the use of tetraethylthiuramdisulfide (TETD) as an adjunct in the treatment of chronic alcoholism. Recently this drug was released to the medical profession, although much...

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DISULFIRAM ICSC: 1438 Date of Peer Review: October 2002. Tetraethylthiuramdisulfide 1,1′-Dithiobis(N,N-diethylthioformamide) bis-(N,N-Diethylthiocarbamoyl)disulfide TETD. CAS # 97-77-8 C10H20N2S4 / ((C2H5)2NCS)2S2 RTECS # JO1225000 Molecular mass: 269.6 UN # EC # 006-079-00-8. PHYSICAL STATE; APPEARANCE: COLOURLESS LIQUID, WITH CHARACTERISTIC ...

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Herein, a continuous synthetic method of tetraethyl thiuram disulfide (TETD) with CO2 as a weak acid reagent in a gas-liquid microdispersion reaction system has been described. A microdispersion reaction system comprising two microreactors for CO2 absorption and diethyldithiocarbamate acid subsequent oxidation reaction was developed. In the first step, the main products of absorption and ...

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Thiram is an organic disulfide that results from the formal oxidative dimerisation of N,N-dimethyldithiocarbamic acid.It is widely used as a fungicidal seed treatment. It has a role as an antibacterial drug, an antiseptic drug and an antifungal agrochemical.

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